Immunity/Digestion/Performance

Bovine Colostrum

First milk from cows rich in antibodies and growth factors that may support immune defenses and gut barrier function in active adults.

Bovine Colostrum

First milk from cows rich in antibodies and growth factors that may support immune defenses and gut barrier function in active adults.

score

evidence

Caution

risk

Overview

Forms

Safety

Stack

Quick Take

Modest evidence for immunity and gut lining in athletes; skip if dairy-sensitive and cost is high.

Bovine colostrum is the nutrient-dense first milk produced by cows immediately after calving, rich in immunoglobulins (IgG), lactoferrin, growth factors (IGF-1, TGF-β), and antimicrobial peptides. Oral supplementation has been studied mainly for immune modulation and gut barrier integrity. Randomized trials suggest it may reduce upper respiratory infections in athletes and attenuate exercise-induced gut permeability. Growth factors have also driven interest in recovery, though effects on body composition are inconsistent. Adults without dairy allergies who train intensely or have gut permeabil

Proven Benefits

Supports immune function

Supports gut barrier integrity

May improve exercise recovery

May reduce inflammation markers

May support lean body mass

May increase IGF-1 levels

Protocol

Amount

10-20 g

Frequency

Once daily, or split into two doses

When

Take on an empty stomach when possible; if using for exercise-related gut stress, dose 30-60 minutes pre-workout.

Onset Time

2-8 weeks for immune and gut benefits; acute pre-exercise dosing studied for gut

Who Should Consider

Endurance or high-intensity athletes

People with exercise-induced GI distress

Those seeking immune support during heavy training

Adults with increased intestinal permeability concerns

How It Works

Immunoglobulins and lactoferrin bind pathogens and modulate mucosal immunity in the gut and upper respiratory tract. Growth factors like IGF-1 and TGF-β may support intestinal epithelial repair and tight-junction integrity, potentially reducing leaky gut. High protein and peptide content provides substrate for tissue repair, though systemic IGF-1 rises from oral colostrum are modest and transient.

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