howtosupplement
Immunity/Heart/Inflammation

Astragalus

Traditional Chinese root herb that may support immune defenses and heart function in adults with recurrent infections.

Astragalus

Astragalus

47
score
C
evidence
Caution
risk
Quick Take

Worth trying for recurrent colds or as an adjunct in heart failure; otherwise benefits are modest.

Astragalus membranaceus is a root used in Traditional Chinese Medicine; the root is sold as capsules, powders, and teas, not as a common food. Its polysaccharides and astragalosides can modulate immune signaling, antioxidant defenses, and endothelial function. The best-supported uses are seasonal immune support, possible adjunct benefit in chronic heart failure, and modest effects on inflammation or glucose in some people. Those with recurrent respiratory infections or selected cardiometabolic conditions are most likely to benefit.

Proven Benefits

01
Reduces cold frequency
02
May improve exercise tolerance
03
May lower hs-CRP and IL-6
04
May improve fasting glucose
05
May support immune cell counts

Protocol

Amount
500-1000 mg
Frequency
Once or twice daily
When
With meals to reduce digestive upset.

Onset Time

2-4 weeks for immune effects; 8-12 weeks for biomarker changes

Who Should Consider

Adults with frequent colds or URTIs
People with chronic heart failure
Adults with prediabetes or insulin resistance
People with elevated inflammatory markers

How It Works

Polysaccharides (APS) and saponins such as astragaloside IV can stimulate macrophages, T cells, and natural killer cells and influence cytokine signaling. Some constituents also show antioxidant and endothelial effects in preclinical studies; cycloastragenol has been studied for telomerase activation, but that is not a reliable effect of standard root extracts.

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